The rambunctious sibling to neighboring restaurant Mani Osteria & Bar, Isalita is a Mexican Cantina. Like our trips to Mexico, Isalita tries to recreate the warmth, laughter and mi casa es su casa spirit of Mexico.

Our menu is inspired by the street stall food found in open air markets in all over Mexico. Regionally unique and fun to eat, with special attention paid to the mercados (markets) of Mexico City where culinary roads converge and morph with cross-cultural influences.  The result is a diverse menu of dishes best shared with friends and colleagues and a cold drink. 

Our beverages include a well-curated list of tequila, mezcal, rum and whisky.  Our specialty cocktails include classics like fresh lime juice margaritas to our imaginative new favorites that use fresh and seasonal ingredients.  Enjoy a frozen blood orange margarita, sample a new tequila, or a glass of wine from Mani Osteria's comprehensive wine list. 

Our food. Our drink. 100% Puro Mexico.  





341A E. Liberty Street
Ann Arbor, MI 48104


T-W 11:30a–10p
Th-Fr 11:30a–11p
Sat 4p-11p
Sun 4p-9p


We take reservations for parties of 5 or more. Tables of this size can be booked on OpenTable, but are of limited availability, so please give us a call and we will do our best to accommodate. We do accept reservations of all size parties at both Mani and Isalita for the following holidays and events:

January Restaurant Week

Valentine's Day

UM Spring Commencement (Friday and Saturday)

June Restaurant Week

You reserve online using OpenTable.  If you can’t find what you are looking for, please do not hesitate to contact us via phone at 734.213.7400 or e-mail

Find a Table

Stop sitting around and join something fun!

Mani Osteria and Isalita restaurant are family owned and operated restaurants located downtown Ann Arbor, Michigan.  We are looking for talented and hardworking team members who are passionate about food, beverage and hospitality.  We seek candidates who are team-focused, self-motivated, detail oriented individuals who enjoy being of service to others and want to contribute to a culture of excellence. 

Please e-mail your resume or stop by in person from 1:30 pm to 4 pm Tuesday through Saturday to meet with a manager.
Prior experience is very helpful, and necessary if you are looking to join our bar team.