The bold sibling to neighboring restaurant Mani Osteria & Bar, Isalita is Ann Arbor’s very own Mexican Cantina. With reverence to our trips to Mexico, Isalita recreates the warmth, laughter and mi casa es su casa spirit of Mexico.

Our menu is inspired by the street stall food found in open air markets throughout Mexico. Regionally unique and fun to eat, we pay special attention to the mercados (markets) of Mexico City where culinary roads converge and morph with cross-cultural influences. The result is a diverse menu of dishes best shared with friends and colleagues and a cold drink. 

Our beverages include a well-curated list of tequila, mezcal, rum, and whisky.  Our specialty cocktails range from classics like fresh lime juice margaritas to our imaginative new favorites utilizing fresh, seasonal ingredients. Enjoy a frozen blood orange margarita, sample a new tequila, or order a glass of wine from Mani Osteria's comprehensive wine list. 





341A E. Liberty Street
Ann Arbor, MI 48104


Tu-Th 11:30a–10p
Fr 11:30a–11p
Sat 12p-11p
Sun 12p-9p

rewards program


We take reservations for parties of 5 or more. Tables of this size are of limited  availability, so please give us a call and we will do our best to accommodate. For smaller parties we suggest that guests take advantage of our 20 minute call ahead guest list. Give us a call when you are 20 minutes away and we will add your name to our list as if you just walked in the door. 

How It Works

Call the restaurant when you are 20 minutes away, and we will add your name to our Guest List. The Guest List guarantees your place in line at the time of your call as if you just walked in the door.  The 20 minute call ahead does not guarantee immediate seating, but does guarantee seating in advance of any guest who just walks in the door (or calls) after you called.  Please note that we will hold your place on the list for only 20 minutes after which we cancel your call ahead status.   Please contact us at 734-213-7400 to add your name to our evening’s list. 

We do accept reservations of all size parties at both Mani and Isalita for the following holidays and events:

January Restaurant Week

Valentine's Day

UM Spring Commencement (Friday and Saturday)

June Restaurant Week


You can reserve online using OpenTable.  If you can’t find what you are looking for, please do not hesitate to contact us via phone at 734.213.7400 or e-mail us.

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Stop sitting around and join something fun!

Mani Osteria and Isalita restaurant are family owned and operated restaurants located downtown Ann Arbor, Michigan.  We are looking for talented and hardworking team members who are passionate about food, beverage and hospitality.  We seek candidates who are team-focused, self-motivated, detail oriented individuals who enjoy being of service to others and want to contribute to a culture of excellence. 

Please e-mail your resume or stop by in person from 1:30 pm to 4 pm Tuesday through Saturday to meet with a manager.
Prior experience is very helpful, and necessary if you are looking to join our bar team.